Abstract Types

CRA
Clinical Review Abstract

LBA
Late-Breaking Abstract

TPS
Trials in Progress Abstract

e
Abstracts selected for publication but not presentation at the Annual Meeting

^
Abstracts granted an exception in accordance with ASCO's Conflict of Interest Policy



Understanding the experience of living with non-small cell lung cancer (NSCLC): A qualitative study.

Sub-category:
Psychosocial Research

Category:
Patient and Survivor Care

Meeting:
2013 ASCO Annual Meeting

Abstract No:
e20618

Citation:
J Clin Oncol 31, 2013 (suppl; abstr e20618)

Publication-only abstracts (abstract number preceded by an "e"), published in conjunction with the 2013 Annual Meeting but not presented at the Meeting, can be found online only.

Author(s): Joanne S. Buzaglo, Christopher Gayer, Rajiv Mallick, Ellyn Micco, Anne Morris, Andrea Stern Ferris, Mitch Golant, Corey J. Langer, C. Daniel Mullins, David Cella; Cancer Support Comunity, Research and Training Institute, Philadelphia, PA; Daiichi Sankyo Co., Ltd., Parsippany, NJ; Fox Chase Cancer Center, Philadelphia, PA; Lungevity, Alexandria, VA; Cancer Support Comunity, Research and Training Institute, Los Angeles, CA; Abramson Cancer Center of the University of Pennsylvania, Philadelphia, PA; University of Maryland School of Pharmacy, Baltimore, MD; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL

Abstract Disclosures


Abstract:

Background: As non-small cell lung cancer (NSCLC) treatments improve and patients live longer, it is increasingly important to develop interventions to help patients live fuller lives. We sought to identify key components of quality of life (QOL) and social support in determining therapeutic decision-making and overall value of life-extension, in patients with NSCLC. Methods: Three semi-structured focus groups (n=16) and telephone interviews (n=15) were conducted and recorded with NSCLC patients (N=31), to explore the full range of symptoms that patients considered important to QOL. A tradeoff format assessed the value of life-extension relative to QOL. Patients were asked to consider a hypothetical treatment option that offered on average a 3 month life extension. Results: Mean age was 61.6 years, 67.6% were female, 77.4% white, 61.3% were not employed/retired, 58.1% were living with a spouse/other, 93.5% had health insurance, and 48.4% were Stage III/IV. Sixty-Eight percent of patients conceptualized emotions and attitudinal orientation as symptoms of NSCLC. Key symptoms/concerns changed over time – 74% of patients reported shock and fear at diagnosis, 55% felt fear or loneliness during the beginning of therapy, 52% successfully connected with other NSCLC patients (peers) and support groups, and reported a positive shift in feelings with social/emotional support from all social networks. 26% of patients reported confusion and isolation during treatment due to education gaps. Financially, 23% of patients reported being adversely impacted by co-pays, 36% by unexpected gaps in coverage, 39% by other bills, and 52% accepted help from any/all sources. The most important factor driving treatment-decision making about life-extending therapy was the somatic (i.e., physical symptom) dimension (84% cited as important), followed by functional (32%), relational (23%), and emotional (10%) factors. Conclusions: Patients with advanced NSCLC tend to conflate emotional well-being post diagnosis with symptoms of their cancer and treatment toxicities. However, somatic QOL concerns, ahead of functional, emotional and relational QOL, emerge as the dominant driver of therapeutic decision-making.

 

  Other Abstracts in this Sub-Category:

 

1. Losing sleep over cancer: Relationships with negative affect, blood pressure, and disease-free interval among women with metastatic breast cancer.

Meeting: 2013 ASCO Annual Meeting Abstract No: 9504 First Author: A. A. Gerry
Category: Patient and Survivor Care - Psychosocial Research

 

2. Preliminary results of RTOG 0831, a randomized, double-blinded, placebo-controlled trial of tadalafil in the prevention of erectile dysfunction in patients treated with radiotherapy for prostate cancer.

Meeting: 2013 ASCO Annual Meeting Abstract No: 9525 First Author: D. Bruner
Category: Patient and Survivor Care - Psychosocial Research

 

3. Psychosocial outcomes among bereaved and non-bereaved parents of children with cancer.

Meeting: 2013 ASCO Annual Meeting Abstract No: 9526 First Author: A. R. Rosenberg
Category: Patient and Survivor Care - Psychosocial Research

 

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